Form: S-8

Initial registration statement for securities to be offered to employees pursuant to employee benefit plans

March 31, 2021

Documents

Exhibit 23.1

Consent of Independent Registered Public Accounting Firm

We consent to the incorporation by reference in the Registration Statement on Form S-8 pertaining to the Inducement and Equity Incentive Plans of Ocuphire Pharma, Inc. of our report dated March 10, 2021, with respect to the consolidated financial statements of Ocuphire Pharma, Inc. included in its Annual Report (Form 10-K) for the year ended December 31, 2020, filed with the Securities and Exchange Commission.

/s/ Ernst & Young LLP

Detroit, Michigan
March 31, 2021