Form: S-3/A

Registration statement under Securities Act of 1933

April 21, 2026


Exhibit 23.1
 

Consent of Independent Registered Public Accounting Firm

 

 
We consent to the reference to our firm under the caption “Experts” in Amendment No. 1 to the Registration Statement (Form S-3) and related Prospectus of Opus Genetics, Inc. for the registration of 7,374,632 shares of its common stock and to the incorporation by reference therein of our report dated March 12, 2026, with respect to the consolidated financial statements of Opus Genetics, Inc. included in its Annual Report (Form 10-K) for the year ended December 31, 2025, filed with the Securities and Exchange Commission.
 

 
/s/ Ernst & Young LLP
 

 
Boston, Massachusetts
 
April 20, 2026